Chemotherapy-induced nail discoloration

Nail discoloration after use of hydroquinone

INTRODUCTION Hydroquinone is the best studied andmost widely used topical depigmenting agent, and represents the gold standard for treatment of disorders of pigmentation. Although ochronosis is a known sequela of long-term hydroquinone use, pigmentation of the nails is rarely a reported side effect. We present a case of identical twins who developed hyperpigmentation of identical nails after th...

Chemotherapy-induced nail changes: an unsightly nuisance.

P.S. is a 53-year-old female patient with stage IIB breast cancer. In November 2000, she received Adriamycin (Pfizer Inc., New York, NY) and Cytoxan (Bristol-Myers Squibb, New York, NY), along with Herceptin (Genentech, Inc., South San Francisco, CA), as part of a clinical trial. In July 2002, the patient was found to have a left supraclavicular axillary recurrence. Because of this recurrence, ...

A Case of Yellow Nail Syndrome with Dramatically Improved Nail Discoloration by Oral Clarithromycin

An 80-year-old woman was admitted to our hospital with pneumonia and exacerbation of sinobronchial syndrome (SBS). She presented with yellow discoloration of the nail beds of all fingers and toes, and her nails were recognized as growing slowly. Chest X-ray revealed bronchiectasis in the bilateral lower lobe and bilateral pleural effusion. We diagnosed her as having yellow nail syndrome (YNS), ...

Nail changes after chemotherapy.

Discoloration of nail beds and skin from minocycline.

224 CMAJ, February 8, 2011, 183(2) © 2011 Canadian Medical Association or its licensors A49-year-old man presented with “bruising” of the fingernails and facial skin. He had recalcitrant rosacea and had undergone bilateral cataract extraction, but had no other significant medical history. He had not no ticed a propensity to bruise, impairment of wound healing or any excessive gingival or nasal ...